Title : Indole-3-carbinol induces tumor cell death: function follows form.

Pub. Date : 2016 Jul

PMID : 27451867






2 Functional Relationships(s)
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1 Furthermore, using small interfering RNA interference to knockdown AHR responsiveness generated a significant resistance to the chemotherapeutic actions of indole-3-carbinol regarding both cell viability and apoptotic activity. indole-3-carbinol aryl hydrocarbon receptor Homo sapiens
2 CONCLUSIONS: Some degree of the cytotoxic and proapoptotic effects of indole-3-carbinol on colon cancer cells is dependent on activation of the aryl hydrocarbon receptor. indole-3-carbinol aryl hydrocarbon receptor Homo sapiens