Title : The human amniotic fluid stem cell secretome effectively counteracts doxorubicin-induced cardiotoxicity.

Pub. Date : 2016 Jul 21

PMID : 27444332






1 Functional Relationships(s)
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1 Mechanistic studies with mouse neonatal ventricular cardiomyocytes (mNVCM) reveal that hAFS-CM inhibition of Dox-elicited senescence and apoptosis is associated with decreased DNA damage, nuclear translocation of NF-kB, and upregulation of the NF-kB controlled genes, Il6 and Cxcl1, promoting mNVCM survival. Doxorubicin interleukin 6 Mus musculus