Title : Formation of OX-1R/CB1R heteromeric complexes in embryonic mouse hypothalamic cells: Effect on intracellular calcium, 2-arachidonoyl-glycerol biosynthesis and ERK phosphorylation.

Pub. Date : 2016 Sep

PMID : 27436148






2 Functional Relationships(s)
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1 FRET and co-immunoprecipitation experiments showed the formation of OX-1R/CB1R heteromers after incubation with OX-A (0.2muM), or OX-A (0.1muM)+ACEA (0.1muM), but not after ACEA (0.2muM), in a manner antagonized by SB-334867 or AM251. arachidonyl-2-chloroethylamide hypocretin (orexin) receptor 1 Mus musculus
2 FRET and co-immunoprecipitation experiments showed the formation of OX-1R/CB1R heteromers after incubation with OX-A (0.2muM), or OX-A (0.1muM)+ACEA (0.1muM), but not after ACEA (0.2muM), in a manner antagonized by SB-334867 or AM251. arachidonyl-2-chloroethylamide hypocretin (orexin) receptor 1 Mus musculus