Title : Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ.

Pub. Date : 2016 Sep

PMID : 27431935






1 Functional Relationships(s)
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1 The mRNA expression of hepatic peroxisome proliferator-activated receptor gamma (PPARgamma) and the natural PPARgamma agonist 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) were significantly increased in the HFD group and significantly suppressed in the HFD-nime group. 14-prostaglandin j2 peroxisome proliferator activated receptor gamma Mus musculus