Title : Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy.

Pub. Date : 2016 Dec

PMID : 27417217






1 Functional Relationships(s)
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1 Functional assay revealed that IRGM knockdown inhibited autophagic flux and increased lipid droplet content in HepG2 and PLC/PRF/5 cells, which were reversed by the autophagy inducer rapamycin administration. Sirolimus heparan sulfate proteoglycan 2 Homo sapiens