Title : Intestinal brush-border Na+/H+ exchanger-3 drives H+-coupled iron absorption in the mouse.

Pub. Date : 2016 Sep 1

PMID : 27390324






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 Divalent metal-ion transporter-1 (DMT1), the principal mechanism by which nonheme iron is taken up at the intestinal brush border, is energized by the H(+)-electrochemical potential gradient. Iron solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 Mus musculus
2 Divalent metal-ion transporter-1 (DMT1), the principal mechanism by which nonheme iron is taken up at the intestinal brush border, is energized by the H(+)-electrochemical potential gradient. Iron solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 Mus musculus
3 Our data point to an important role for NHE3 in generating the H(+) gradient that drives DMT1-mediated iron uptake at the intestinal brush border. Iron solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 Mus musculus