Title : Efficacy of Oral Curcuminoid Fraction from Curcuma xanthorrhiza and Curcuminoid Cider in High-cholesterol Fed Rats.

Pub. Date : 2016 Jul-Sep

PMID : 27365981






6 Functional Relationships(s)
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1 OBJECTIVE: The present work was aimed to study the efficacy of curcuminoid fraction from Curcuma xanthorrhiza and its curcuminoid cider in reducing blood cholesterol level and four genes related to oxidative stress, including cluster of differentiation 44 (CD44), intercellular adhesion molecule 1 (ICAM-1), inducible nitric oxide synthase (iNOS), and lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in high-cholesterol fed rats in vivo. curcuminoid intercellular adhesion molecule 1 Rattus norvegicus
2 OBJECTIVE: The present work was aimed to study the efficacy of curcuminoid fraction from Curcuma xanthorrhiza and its curcuminoid cider in reducing blood cholesterol level and four genes related to oxidative stress, including cluster of differentiation 44 (CD44), intercellular adhesion molecule 1 (ICAM-1), inducible nitric oxide synthase (iNOS), and lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in high-cholesterol fed rats in vivo. curcuminoid intercellular adhesion molecule 1 Rattus norvegicus
3 OBJECTIVE: The present work was aimed to study the efficacy of curcuminoid fraction from Curcuma xanthorrhiza and its curcuminoid cider in reducing blood cholesterol level and four genes related to oxidative stress, including cluster of differentiation 44 (CD44), intercellular adhesion molecule 1 (ICAM-1), inducible nitric oxide synthase (iNOS), and lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in high-cholesterol fed rats in vivo. curcuminoid intercellular adhesion molecule 1 Rattus norvegicus
4 OBJECTIVE: The present work was aimed to study the efficacy of curcuminoid fraction from Curcuma xanthorrhiza and its curcuminoid cider in reducing blood cholesterol level and four genes related to oxidative stress, including cluster of differentiation 44 (CD44), intercellular adhesion molecule 1 (ICAM-1), inducible nitric oxide synthase (iNOS), and lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in high-cholesterol fed rats in vivo. curcuminoid intercellular adhesion molecule 1 Rattus norvegicus
5 Real-time PCR data showed both curcuminoid fractions (100 and 300 mg/kg) and curcuminoid cider (1 and 2% v/v) inhibited the gene expression of CD44, ICAM-1, iNOS, and LOX-1, indicating their hypocholesterolemic effects via attenuating genes related to oxidative stress in rats in vivo. curcuminoid intercellular adhesion molecule 1 Rattus norvegicus
6 Real-time PCR data showed both curcuminoid fractions (100 and 300 mg/kg) and curcuminoid cider (1 and 2% v/v) inhibited the gene expression of CD44, ICAM-1, iNOS, and LOX-1, indicating their hypocholesterolemic effects via attenuating genes related to oxidative stress in rats in vivo. curcuminoid intercellular adhesion molecule 1 Rattus norvegicus