| Protein Name | intercellular adhesion molecule 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25464 |
| Gene Symbol | Icam1 |
| UniProt | Q00238 (ICAM1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
647
Total Number of Articles : 894 |
Description |
intercellular adhesion molecule 1 |
| Gene Summary |
Enables integrin binding activity. Involved in several processes, including cellular response to cytokine stimulus; gonad development; and positive regulation of metabolic process. Located in cell surface and extracellular space. Used to study diabetic angiopathy; mesenteric vascular occlusion; nephritis; pre-eclampsia; and uveitis. Biomarker of several diseases, including cerebrovascular disease (multiple); colitis (multiple); kidney failure (multiple); lung disease (multiple); and pancreatitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); biliary atresia; diabetic retinopathy; inflammatory bowel disease (multiple); and multiple myeloma. Orthologous to human ICAM1 (intercellular adhesion molecule 1). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |