Title : Reactive oxygen species: sources, consequences and targeted therapy in type 2 diabetes.

Pub. Date : 2017 Feb

PMID : 27356044






2 Functional Relationships(s)
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1 The intracellular reactive oxygen species (ROS) leads to oxidative stress and it is raised from the mitochondria as well as by activation of five major pathways: increased polyol pathway flux, activation of protein kinase C (PKC) pathway, increased formation of advanced glycation end products (AGEs), over activity of hexosamine pathway and increased production of angiotensin II. Reactive Oxygen Species angiotensinogen Homo sapiens
2 The intracellular reactive oxygen species (ROS) leads to oxidative stress and it is raised from the mitochondria as well as by activation of five major pathways: increased polyol pathway flux, activation of protein kinase C (PKC) pathway, increased formation of advanced glycation end products (AGEs), over activity of hexosamine pathway and increased production of angiotensin II. Reactive Oxygen Species angiotensinogen Homo sapiens