Title : Site-specific covalent modifications of human insulin by catechol estrogens: Reactivity and induced structural and functional changes.

Pub. Date : 2016 Jun 29

PMID : 27353345






1 Functional Relationships(s)
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1 Upon co-incubation, intact insulin formed a substantial number of adducts with one or multiple CEs via covalent conjugation at its Cys 7 in the A or B chain, as well as at His10 or Lys29 in the B chain. Cysteine insulin Homo sapiens