Pub. Date : 2016
PMID : 27347312
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Isoflurane attenuates lipopolysaccharide-induced acute lung injury by inhibiting ROS-mediated NLRP3 inflammasome activation. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Rattus norvegicus |
| 2 | Mechanistically, ISO reduced NLRP3 activation and caspase-1 activity in a reactive oxygen species (ROS)-dependent manner. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Rattus norvegicus |
| 3 | Mechanistically, ISO reduced NLRP3 activation and caspase-1 activity in a reactive oxygen species (ROS)-dependent manner. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Rattus norvegicus |
| 4 | Overall, these results indicate that ISO post-conditioning alleviated LPS-induced ALI possibly by inhibiting ROS-mediated NLRP3 inflammasome activation. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Rattus norvegicus |