Title : Probucol inhibits LPS-induced microglia activation and ameliorates brain ischemic injury in normal and hyperlipidemic mice.

Pub. Date : 2016 Aug

PMID : 27345627






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1 RESULTS: In LPS-treated BV2 cells and primary microglial cells, pretreatment with probucol (1, 5, 10 mumol/L) dose-dependently inhibited the release of NO, PGE2, IL-1beta and IL-6, which occurred at the transcription levels. Probucol interleukin 6 Mus musculus