Pub. Date : 2016 Mar
PMID : 27263286
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: 10 mumol/L arsenic trioxide can decreased the cell viability, while cell apoptosis rate, ROS level, HO-1 and Nrf2 protein expression was increased (P < 0.05). | Arsenic Trioxide | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 2 | When compared with arsenic trioxide alone, co-treatment of arsenic trioxide with aspirin in different concentration (0, 0.1, 1.0, 2.5, 5.0 mmol/L) exhibited dual effects in intracellular ROS level, HO-1 and Nrf2 expression. | Arsenic Trioxide | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 3 | On the contrary, 5 mmol/L aspirin could increase the sensitivity of HepG2 to arsenic trioxide through enhancing the arsenic trioxide-induced apoptosis by ROS accumulation resulting in inhibiting the Nrf2-HO-1 pathway. | Arsenic Trioxide | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 4 | On the contrary, 5 mmol/L aspirin could increase the sensitivity of HepG2 to arsenic trioxide through enhancing the arsenic trioxide-induced apoptosis by ROS accumulation resulting in inhibiting the Nrf2-HO-1 pathway. | Arsenic Trioxide | NFE2 like bZIP transcription factor 2 | Homo sapiens |