Title : Decreased sensitivity to paroxetine-induced inhibition of peripheral blood mononuclear cell growth in depressed and antidepressant treatment-resistant patients.

Pub. Date : 2016 May 31

PMID : 27244236






1 Functional Relationships(s)
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1 A significantly lower expression of integrin beta-3 (ITGB3), a co-factor of the SERT, was observed in the PBMCs of MDD patients prior to treatment onset compared with healthy controls, and may explain their lower paroxetine sensitivity. Paroxetine solute carrier family 6 member 4 Homo sapiens