Pub. Date : 2016 Aug 3
PMID : 27235579
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | c-Jun-N-terminal kinase 1 is necessary for nicotine-induced enhancement of contextual fear conditioning. | Nicotine | mitogen-activated protein kinase 8 | Mus musculus |
| 2 | The effects of nicotine on learning may involve recruitment of signaling through the c-Jun N-terminal kinase family (JNK 1-3). | Nicotine | mitogen-activated protein kinase 8 | Mus musculus |
| 3 | Learning in the presence of acute nicotine increases the transcription of mitogen-activated protein kinase 8 (MAPK8, also known as JNK1), likely through a CREB-dependent mechanism. | Nicotine | mitogen-activated protein kinase 8 | Mus musculus |
| 4 | Learning in the presence of acute nicotine increases the transcription of mitogen-activated protein kinase 8 (MAPK8, also known as JNK1), likely through a CREB-dependent mechanism. | Nicotine | mitogen-activated protein kinase 8 | Mus musculus |
| 5 | Learning in the presence of acute nicotine increases the transcription of mitogen-activated protein kinase 8 (MAPK8, also known as JNK1), likely through a CREB-dependent mechanism. | Nicotine | mitogen-activated protein kinase 8 | Mus musculus |
| 6 | The functional significance of JNK1 in the effects of acute nicotine on learning, however, is unknown. | Nicotine | mitogen-activated protein kinase 8 | Mus musculus |
| 7 | The current studies undertook a backward genetic approach to determine the functional contribution JNK1 protein makes to nicotine-enhanced contextual fear conditioning. | Nicotine | mitogen-activated protein kinase 8 | Mus musculus |
| 8 | These data suggest that JNK1 may be recruited by nicotine and is functionally necessary for the acute effects of nicotine on learning and memory. | Nicotine | mitogen-activated protein kinase 8 | Mus musculus |
| 9 | These data suggest that JNK1 may be recruited by nicotine and is functionally necessary for the acute effects of nicotine on learning and memory. | Nicotine | mitogen-activated protein kinase 8 | Mus musculus |