Pub. Date : 2016 Jul
PMID : 27220352
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Curcumin reduced FFA influx into the liver by blocking FFA trafficking, and then prevented diacylglycerol deposits and PKCepsilon translocation in the liver, resultantly improving insulin action in the suppression of hepatic gluconeogenesis. | Curcumin | insulin | Homo sapiens |
2 | Curcumin decreased adipose lipolysis by attenuating ER stress through the cAMP/PKA pathway, reduced FFA influx into the liver by blocking FFA trafficking, and thereby improved insulin sensitivity to inhibit hepatic glucose production. | Curcumin | insulin | Homo sapiens |
3 | These findings suggested a novel pathway of curcumin to prevent lipid deposits and insulin resistance in liver by beneficial regulation of adipose function. | Curcumin | insulin | Homo sapiens |