Pub. Date : 2016
PMID : 27213050
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 1,3-Propanediol binds inside the water-conducting pore of aquaporin 4: Does this efficacious inhibitor have sufficient potency? | 1,3-propanediol | aquaporin 4 | Homo sapiens |
| 2 | We compute the binding affinities of 1,2-ethanediol (EDO) and 1,3-propanediol (PDO) inside the AQP4 conducting pore and identify the specificities of the interactions. | 1,3-propanediol | aquaporin 4 | Homo sapiens |
| 3 | Considering the fact that PDO is classified by the US Food and Drug Administration as generally safe, we predict that 1,3-propanediol could be an effective drug for brain edema and other AQP4-correlated neurological conditions. | 1,3-propanediol | aquaporin 4 | Homo sapiens |