Title : P-Glycoprotein Activity in Steroid-Responsive vs. Steroid-Resistant Nephrotic Syndrome.

Pub. Date : 2016 Nov

PMID : 27193461






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 P-Glycoprotein Activity in Steroid-Responsive vs. Steroid-Resistant Nephrotic Syndrome. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
2 P-Glycoprotein Activity in Steroid-Responsive vs. Steroid-Resistant Nephrotic Syndrome. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
3 RESULTS: P-gp activity was significantly higher in steroid-resistant than steroid-sensitive cases. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
4 RESULTS: P-gp activity was significantly higher in steroid-resistant than steroid-sensitive cases. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
5 CONCLUSIONS: P-gp can be used as a predictor of outcome, as a part of laboratory evaluation of the cases before starting steroid therapy, so as to determine whether to use alternative line of therapy or use one of the P-gp inhibitors with steroid therapy. Steroids ATP binding cassette subfamily B member 1 Homo sapiens
6 CONCLUSIONS: P-gp can be used as a predictor of outcome, as a part of laboratory evaluation of the cases before starting steroid therapy, so as to determine whether to use alternative line of therapy or use one of the P-gp inhibitors with steroid therapy. Steroids ATP binding cassette subfamily B member 1 Homo sapiens