Title : A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis.

Pub. Date : 2016 Jun 21

PMID : 27191895






1 Functional Relationships(s)
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1 Mice given GSK1016790A showed increased phosphorylation of eNOS and AMPK in the aorta and decreased leukocyte adhesion to TNF-alpha-inflamed endothelium. N-(1-((4-(2-(((2,4-dichlorophenyl)sulfonyl)amino)-3-hydroxypropanoyl)-1-piperazinyl)carbonyl)-3-methylbutyl)-1-benzothiophene-2-carboxamide tumor necrosis factor Mus musculus