Title : Serotonin 5-HT1B receptor-mediated calcium influx-independent presynaptic inhibition of GABA release onto rat basal forebrain cholinergic neurons.

Pub. Date : 2016 Jul

PMID : 27177433






2 Functional Relationships(s)
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1 Serotonin 5-HT1B receptor-mediated calcium influx-independent presynaptic inhibition of GABA release onto rat basal forebrain cholinergic neurons. gamma-Aminobutyric Acid 5-hydroxytryptamine receptor 1B Rattus norvegicus
2 These results suggest that activation of presynaptic 5-HT1B receptors on the terminals of GABAergic afferents to basal forebrain cholinergic neurons inhibits GABA release in Ca(2+) influx-independent manner by modulation of K(+) channels, leading to enhancement of neuronal activities. gamma-Aminobutyric Acid 5-hydroxytryptamine receptor 1B Rattus norvegicus