Protein Name euchromatic histone lysine methyltransferase 2
Organism Homo sapiens
Gene ID 10919
Gene Symbol

EHMT2

UniProt Q96KQ7 (EHMT2_HUMAN), A0A024RCN9 (A0A024RCN9_HUMAN), A2ABF8 (A2ABF8_HUMAN), B7Z852 (B7Z852_HUMAN), Q59FM7 (Q59FM7_HUMAN)
Relationships Total Number of functionally related compound(s) : 137
Total Number of Articles : 212
Description

euchromatic histone lysine methyltransferase 2

Gene Summary

This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

synonyms
  • histone-lysine N-methyltransferase EHMT2
  • G9A histone methyltransferase
  • H3-K9-HMTase 3
Click to show/hide the synonyms
Properties