Pub. Date : 2016 Jun 25
PMID : 27174133
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenite-induced alteration in heart Nrf-2, HO-1, Smad-3, and TGF-beta mRNA expression were significantly restored (p < 0.05) by naringin (40 and 80 mg/kg) treatment. | arsenite | heme oxygenase 1 | Rattus norvegicus |
| 2 | CONCLUSION: The results of present investigation suggest that naringin ameliorates arsenite-induced cardiotoxicity via modulation of TGF-beta/Smad-3 and Nrf-2/HO-1 pathways along with a reduction in myocardial apoptosis. | arsenite | heme oxygenase 1 | Rattus norvegicus |