Title : Celastrol-Induced Suppression of the MiR-21/ERK Signalling Pathway Attenuates Cardiac Fibrosis and Dysfunction.

Pub. Date : 2016

PMID : 27160852






1 Functional Relationships(s)
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1 RESULTS: Celastrol treatment reduced the increased collagen deposition and down-regulated alpha-smooth muscle actin (alpha-SMA), atrial natriuretic peptide (ANP), brain natriuretic peptides (BNP), beta-myosin heavy chain (beta-MHC), miR-21 and p-ERK/ERK. celastrol natriuretic peptide type B Mus musculus