| Protein Name | natriuretic peptide type B |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18158 |
| Gene Symbol | Nppb |
| UniProt | P40753 (ANFB_MOUSE), Q54AE9 (Q54AE9_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
157
Total Number of Articles : 153 |
Description |
natriuretic peptide type B |
| Gene Summary |
This gene encodes a secreted protein that belongs to the family of natriuretic peptides. Its precursor protein is processed to generate the active mature peptide. The mature peptide is a cardiac hormone that plays a role in ventricular remodeling as well as blood pressure regulation. Mice lacking this gene exhibit cardiac fibrosis. In humans this gene is associated with congestive heart failure, low bone-mineral density and postmenopausal osteoporosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013] |
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| Properties | |