Title : Celastrol Induces Cell Apoptosis and Inhibits the Expression of the AML1-ETO/C-KIT Oncoprotein in t(8;21) Leukemia.

Pub. Date : 2016 Apr 30

PMID : 27144550






1 Functional Relationships(s)
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1 In addition, we found that celastrol downregulated the AML1-ETO fusion protein, therefore downregulating C-KIT kinases and inhibiting AKT, STAT3 and Erk1/2. celastrol mitogen-activated protein kinase 3 Homo sapiens