Title : GQ-16, a TZD-Derived Partial PPARĪ³ Agonist, Induces the Expression of Thermogenesis-Related Genes in Brown Fat and Visceral White Fat and Decreases Visceral Adiposity in Obese and Hyperglycemic Mice.

Pub. Date : 2016

PMID : 27138164






2 Functional Relationships(s)
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1 GQ-16, a TZD-Derived Partial PPARgamma Agonist, Induces the Expression of Thermogenesis-Related Genes in Brown Fat and Visceral White Fat and Decreases Visceral Adiposity in Obese and Hyperglycemic Mice. tzd peroxisome proliferator activated receptor gamma Mus musculus
2 METHODS: Male Swiss mice with obesity and hyperglycemia induced by high fat diet were treated with vehicle, rosiglitazone (4 mg/kg/d) or the TZD-derived partial PPARgamma agonist GQ-16 (40 mg/kg/d) for 14 days. tzd peroxisome proliferator activated receptor gamma Mus musculus