Title : A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancer.

Pub. Date : 2016 Nov 24

PMID : 27132509






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The EML4-ALK-mediated upregulation of HIF1alpha, HK2 and glycolytic metabolism was also highly active in vivo as demonstrated by fluorodeoxyglucose-positron emission tomography imaging of xenografts grown from EML4-ALK-positive NSCLC cells. Fluorodeoxyglucose F18 hypoxia inducible factor 1 subunit alpha Homo sapiens