Title : S100A4 drives non-small cell lung cancer invasion, associates with poor prognosis, and is effectively targeted by the FDA-approved anti-helminthic agent niclosamide.

Pub. Date : 2016 Jun 7

PMID : 27127879






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 S100A4 drives non-small cell lung cancer invasion, associates with poor prognosis, and is effectively targeted by the FDA-approved anti-helminthic agent niclosamide. Niclosamide S100 calcium binding protein A4 Homo sapiens
2 Niclosamide, a reported inhibitor of S100A4, blocks expression and function of S100A4 with a reduction in proliferation, invasion and NF-kappaB-mediated MMP9 expression. Niclosamide S100 calcium binding protein A4 Homo sapiens
3 Niclosamide, a reported inhibitor of S100A4, blocks expression and function of S100A4 with a reduction in proliferation, invasion and NF-kappaB-mediated MMP9 expression. Niclosamide S100 calcium binding protein A4 Homo sapiens