Protein Name S100 calcium binding protein A4
Organism Homo sapiens
Gene ID 6275
Gene Symbol


UniProt P26447 (S10A4_HUMAN)
Relationships Total Number of functionally related compound(s) : 156
Total Number of Articles : 227

S100 calcium binding protein A4

Gene Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

  • protein S100-A4
  • S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)
  • calcium placental protein
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