Title : Trichostatin A potentiates genistein-induced apoptosis and reverses EMT in HEp2 cells.

Pub. Date : 2016 Jun

PMID : 27121018






3 Functional Relationships(s)
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1 Treatment of the HEp-2 cells with genistein and TSA led to a significant reduction in the phosphorylation of Akt and activation of its downstream target, and resulted in peroxisome proliferator-activated receptor-gamma cleavage, increased expression of B cell lymphoma-2 (Bcl-2)-associated X protein and reduced the expression of Bcl-2. trichostatin A BCL2 apoptosis regulator Homo sapiens
2 Treatment of the HEp-2 cells with genistein and TSA led to a significant reduction in the phosphorylation of Akt and activation of its downstream target, and resulted in peroxisome proliferator-activated receptor-gamma cleavage, increased expression of B cell lymphoma-2 (Bcl-2)-associated X protein and reduced the expression of Bcl-2. trichostatin A BCL2 apoptosis regulator Homo sapiens
3 Treatment of the HEp-2 cells with genistein and TSA led to a significant reduction in the phosphorylation of Akt and activation of its downstream target, and resulted in peroxisome proliferator-activated receptor-gamma cleavage, increased expression of B cell lymphoma-2 (Bcl-2)-associated X protein and reduced the expression of Bcl-2. trichostatin A BCL2 apoptosis regulator Homo sapiens