Title : Extracellular cathepsin S and intracellular caspase 1 activation are surrogate biomarkers of particulate-induced lysosomal disruption in macrophages.

Pub. Date : 2016 Apr 23

PMID : 27108091






1 Functional Relationships(s)
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1 RESULTS: We demonstrate that exposure to silica, alum and polystyrene particulates induces IL-1beta release from macrophages, through lysosomal destabilization. Silicon Dioxide interleukin 1 beta Mus musculus