Title : The Apoptotic Effect of Ursolic Acid on SK-Hep-1 Cells is Regulated by the PI3K/Akt, p38 and JNK MAPK Signaling Pathways.

Pub. Date : 2016 Apr 20

PMID : 27104510






1 Functional Relationships(s)
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1 The western blot results revealed that exposure to UA was associated with decreased expression of the anti-apoptotic proteins Mcl-1, Bcl-xL, Bcl-2, and TCTP and increased expression of apoptosis-related proteins TNF-alpha, Fas, FADD, Bax, cleaved caspase-3, caspase-8, caspase-9, and PARP. ursolic acid MCL1 apoptosis regulator, BCL2 family member Homo sapiens