Title : Guiding synovial inflammation by macrophage phenotype modulation: an in vitro study towards a therapy for osteoarthritis.

Pub. Date : 2016 Sep

PMID : 27095417






2 Functional Relationships(s)
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1 RESULTS: Dexamethasone had an anti-inflammatory effect on IFNgamma + TNFalpha stimulated and osteoarthritic synovium, likely due to suppression of pro-inflammatory M(IFNgamma + TNFalpha) macrophages while enhancing anti-inflammatory M(IL4) and M(IL10) macrophages. Dexamethasone interferon gamma Homo sapiens
2 RESULTS: Dexamethasone had an anti-inflammatory effect on IFNgamma + TNFalpha stimulated and osteoarthritic synovium, likely due to suppression of pro-inflammatory M(IFNgamma + TNFalpha) macrophages while enhancing anti-inflammatory M(IL4) and M(IL10) macrophages. Dexamethasone interferon gamma Homo sapiens