Pub. Date : 2016 May
PMID : 27090797
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | HDAC6-mediated EGFR stabilization and activation restrict cell response to sorafenib in non-small cell lung cancer cells. | Sorafenib | histone deacetylase 6 | Homo sapiens |
| 2 | Overexpression of HDAC6 confers resistance to sorafenib in NSCLC cells. | Sorafenib | histone deacetylase 6 | Homo sapiens |
| 3 | Inhibition of HDAC6 with selective inhibitors synergizes with sorafenib to kill NSCLC cells via inhibition of sorafenib-mediated EGFR pathway activation. | Sorafenib | histone deacetylase 6 | Homo sapiens |
| 4 | Inhibition of HDAC6 with selective inhibitors synergizes with sorafenib to kill NSCLC cells via inhibition of sorafenib-mediated EGFR pathway activation. | Sorafenib | histone deacetylase 6 | Homo sapiens |