Title : Liprotides made of α-lactalbumin and cis fatty acids form core-shell and multi-layer structures with a common membrane-targeting mechanism.

Pub. Date : 2016 Jul

PMID : 27068540






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Liprotides made of alpha-lactalbumin and cis fatty acids form core-shell and multi-layer structures with a common membrane-targeting mechanism. liprotides lactalbumin alpha Homo sapiens
2 We recently showed that aLA and several other proteins all form protein-OA complexes called liprotides with a generic structure consisting of a micellar OA core surrounded by a shell of partially denatured protein. liprotides lactalbumin alpha Homo sapiens
3 All liprotides containing cis-FA form both small and large species, which all consist of partially denatured aLA, though the overall shape of the species differs. liprotides lactalbumin alpha Homo sapiens
4 Small liprotides have a simple core-shell structure while the larger liprotides are multi-layered, i.e. they have an additional layer of both FA and aLA surrounding the outside of the core-shell structure. liprotides lactalbumin alpha Homo sapiens
5 All liprotides can transfer their entire FA content to vesicles, releasing aLA as monomers and softening the lipid membrane. liprotides lactalbumin alpha Homo sapiens