Protein Name lactalbumin alpha
Organism Homo sapiens
Gene ID 3906
Gene Symbol

LALBA

UniProt P00709 (LALBA_HUMAN), A0A080YV01 (A0A080YV01_HUMAN)
Relationships Total Number of functionally related compound(s) : 373
Total Number of Articles : 590
Description

lactalbumin alpha

Gene Summary

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008]

synonyms
  • alpha-lactalbumin
  • lactose synthase B protein
  • lysozyme G
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Properties