Title : Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury.

Pub. Date : 2017 Jan

PMID : 27052460






4 Functional Relationships(s)
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1 Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury. Oxysterols nuclear receptor subfamily 1, group H, member 3 Mus musculus
2 The above oxysterols are physiological ligands of liver X receptors (LXRs), and SULT2B1b suppressed oxysterol-induced LXR activation. Oxysterols nuclear receptor subfamily 1, group H, member 3 Mus musculus
3 The above oxysterols are physiological ligands of liver X receptors (LXRs), and SULT2B1b suppressed oxysterol-induced LXR activation. Oxysterols nuclear receptor subfamily 1, group H, member 3 Mus musculus
4 Our data indicate that upregulation of SULT2B1b might promote HOC proliferation and aggravate liver injury via the suppression of oxysterol-induced LXR activation in chemically induced mouse liver injury. Oxysterols nuclear receptor subfamily 1, group H, member 3 Mus musculus