Pub. Date : 2016
PMID : 27045516
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mefloquine was shown to be a P-gp inhibitor affecting our P-gp substrate, Rhodamine 123, although none of the other drugs impacted upon rhodamine123 transport rates. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens |
2 | Mefloquine was shown to be a P-gp inhibitor affecting our P-gp substrate, Rhodamine 123, although none of the other drugs impacted upon rhodamine123 transport rates. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens |
3 | In conclusion, mefloquine is a P-gp inhibitor and methylene blue is a partial substrate; methylene blue may have increased absorption if co-administered with such P-gp inhibitors. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens |
4 | In conclusion, mefloquine is a P-gp inhibitor and methylene blue is a partial substrate; methylene blue may have increased absorption if co-administered with such P-gp inhibitors. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens |
5 | An upregulation of P-gp was observed when artemisone and dihydroartemisinin were co-incubated with mefloquine and amodiaquine. | Mefloquine | ATP binding cassette subfamily B member 1 | Homo sapiens |