Pub. Date : 2016 May
PMID : 27035875
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By immunofluorescence staining, subcellular fractionation and western blotting, the present study demonstrated that curcumin was able to induce G2/M cell cycle arrest and apoptosis by increasing the expression levels of cyclin G2, cleaved caspase-3 and Fas ligand (FasL), and decreasing the expression of cyclin-dependent kinase 1 (CDK1). | Curcumin | cyclin dependent kinase 1 | Homo sapiens |
| 2 | By immunofluorescence staining, subcellular fractionation and western blotting, the present study demonstrated that curcumin was able to induce G2/M cell cycle arrest and apoptosis by increasing the expression levels of cyclin G2, cleaved caspase-3 and Fas ligand (FasL), and decreasing the expression of cyclin-dependent kinase 1 (CDK1). | Curcumin | cyclin dependent kinase 1 | Homo sapiens |
| 3 | Furthermore, following knockdown of FoxO1 expression in curcumin-treated U87 cells using FoxO1 small interfering RNA, the expression levels of cyclin G2, cleaved caspase-3 and FasL were inhibited; however, the expression levels of CDK1 were not markedly altered. | Curcumin | cyclin dependent kinase 1 | Homo sapiens |