Pub. Date : 2016 Jul
PMID : 27031121
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Patients with prolonged effect of succinylcholine or mivacurium had novel mutations in the butyrylcholinesterase gene. | Mivacurium | butyrylcholinesterase | Homo sapiens |
| 2 | INTRODUCTION: Mutations in the butyrylcholinesterase enzyme (BChE) can result in prolonged duration of action of the neuromuscular blocking agents, succinylcholine and mivacurium, as BChE hydrolyses these drugs. | Mivacurium | butyrylcholinesterase | Homo sapiens |
| 3 | INTRODUCTION: Mutations in the butyrylcholinesterase enzyme (BChE) can result in prolonged duration of action of the neuromuscular blocking agents, succinylcholine and mivacurium, as BChE hydrolyses these drugs. | Mivacurium | butyrylcholinesterase | Homo sapiens |
| 4 | INTRODUCTION: Mutations in the butyrylcholinesterase enzyme (BChE) can result in prolonged duration of action of the neuromuscular blocking agents, succinylcholine and mivacurium, as BChE hydrolyses these drugs. | Mivacurium | butyrylcholinesterase | Homo sapiens |
| 5 | The aim of this study was to describe novel mutations in the butyrylcholinesterase gene (BCHE) in patients who have experienced prolonged duration of action of mivacurium or succinylcholine. | Mivacurium | butyrylcholinesterase | Homo sapiens |
| 6 | The aim of this study was to describe novel mutations in the butyrylcholinesterase gene (BCHE) in patients who have experienced prolonged duration of action of mivacurium or succinylcholine. | Mivacurium | butyrylcholinesterase | Homo sapiens |
| 7 | METHODS: The Danish Cholinesterase Research Unit registers patients with prolonged duration of action to succinylcholine and mivacurium. | Mivacurium | butyrylcholinesterase | Homo sapiens |
| 8 | CONCLUSION: We have found seven new variants of the BCHE, which seem to reduce the activity of BChE in patients undergoing anaesthesia involving succinylcholine or mivacurium. | Mivacurium | butyrylcholinesterase | Homo sapiens |
| 9 | CONCLUSION: We have found seven new variants of the BCHE, which seem to reduce the activity of BChE in patients undergoing anaesthesia involving succinylcholine or mivacurium. | Mivacurium | butyrylcholinesterase | Homo sapiens |