Title : Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease.

Pub. Date : 2016 Mar 30

PMID : 27030596






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-beta clearance and aggregation in Alzheimer"s disease. Heparitin Sulfate amyloid beta precursor protein Homo sapiens
2 Cell surface heparan sulfates (HSs), expressed on all cell types including neurons, have been implicated in several features in the pathogenesis of AD including its colocalization with amyloid plaques and modulatory role in Abeta aggregation. Heparitin Sulfate amyloid beta precursor protein Homo sapiens