Pub. Date : 2016 Jun 10
PMID : 27019345
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The models were used to simulate inhibition of the MATE1, MATE2-K, OCT1 and OCT2 mediated transport of metformin by cimetidine. | Cimetidine | POU class 2 homeobox 2 | Homo sapiens |
| 2 | The observed AUC ratio could only be recovered with this model when the cimetidine Ki for OCT2 was decreased 1000-fold or the Ki"s for both OCT1 and OCT2 were decreased 500-fold. | Cimetidine | POU class 2 homeobox 2 | Homo sapiens |
| 3 | The observed AUC ratio could only be recovered with this model when the cimetidine Ki for OCT2 was decreased 1000-fold or the Ki"s for both OCT1 and OCT2 were decreased 500-fold. | Cimetidine | POU class 2 homeobox 2 | Homo sapiens |