Title : Rational Design, Synthesis, and Biological Evaluation of 7-Azaindole Derivatives as Potent Focused Multi-Targeted Kinase Inhibitors.

Pub. Date : 2016 Apr 28

PMID : 27010810






1 Functional Relationships(s)
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1 Efforts were made to improve a series of potent dual ABL/SRC inhibitors based on a 7-azaindole core with the aim of developing compounds that demonstrate a wider activity on selected oncogenic kinases. 7-azaindole dimer SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens