Title : Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization.

Pub. Date : 2016 Mar 18

PMID : 26988603






1 Functional Relationships(s)
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1 Fluvoxamine inhibited serum-induced ruffle formation, cell migration, and invasion of human GBM and glioma stem cells in vitro by suppressing both FAK and Akt/mammalian target of rapamycin signaling. Fluvoxamine mechanistic target of rapamycin kinase Homo sapiens