Title : Sinomenine prevents metastasis of human osteosarcoma cells via S phase arrest and suppression of tumor-related neovascularization and osteolysis through the CXCR4-STAT3 pathway.

Pub. Date : 2016 May

PMID : 26983669






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sinomenine inhibited invasion by suppressing CXCR4 and STAT3 phosphorylation then downregulating the expression of MMP-2, MMP-9, RANKL, VEGF downstream. sinomenine matrix metallopeptidase 9 Homo sapiens