Title : Chiral analysis of carvedilol and its metabolites hydroxyphenyl carvedilol and O-desmethyl carvedilol in human plasma by liquid chromatography-tandem mass spectrometry: Application to a clinical pharmacokinetic study.

Pub. Date : 2016 Mar 15

PMID : 26927877






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Carvedilol is metabolized mainly by glucuronidation and, to a lesser extent, by CYP2D6 to hydroxyphenyl carvedilol (OHC) and by CYP2C9 to O-desmethyl carvedilol (DMC). desmethylcarvedilol cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 Carvedilol is metabolized mainly by glucuronidation and, to a lesser extent, by CYP2D6 to hydroxyphenyl carvedilol (OHC) and by CYP2C9 to O-desmethyl carvedilol (DMC). desmethylcarvedilol cytochrome P450 family 2 subfamily C member 9 Homo sapiens