Title : L-cysteine protects intestinal integrity, attenuates intestinal inflammation and oxidant stress, and modulates NF-κB and Nrf2 pathways in weaned piglets after LPS challenge.

Pub. Date : 2016 Apr

PMID : 26921254






3 Functional Relationships(s)
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1 L-cysteine protects intestinal integrity, attenuates intestinal inflammation and oxidant stress, and modulates NF-kappaB and Nrf2 pathways in weaned piglets after LPS challenge. Cysteine NFE2 like bZIP transcription factor 2 Homo sapiens
2 Finally, a diet supplemented withL-cys inhibited NF-kappaB(p65) nuclear translocation and elevated NF erythroid 2-related factor 2 (Nrf2) translocation compared with the LPS group. Cysteine NFE2 like bZIP transcription factor 2 Homo sapiens
3 Collectively, our results indicated the protective function ofL-cys on intestinal mucosa barrier may closely associated with its anti-inflammation, antioxidant and regulating effect on the NF-kappaB and Nrf2 signaling pathways. Cysteine NFE2 like bZIP transcription factor 2 Homo sapiens