Title : Dietary Luteolin Reduces Proinflammatory Microglia in the Brain of Senescent Mice.

Pub. Date : 2016 Aug

PMID : 26918466






2 Functional Relationships(s)
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1 In saline-treated mice fed control diet, aging increased the proportion of microglia that stained for MHC class II (<3% for adults vs. 23% for aged), IL-1beta (<2% for adults vs. 25% for aged), and IL-6 (<2% for adults vs. 25% for aged), indicating an age-related increase in proinflammatory microglia. Sodium Chloride interleukin 6 Mus musculus
2 In saline-treated aged mice fed luteolin, the proportion of microglia that stained for MHC class II, IL-1beta, and IL-6 was reduced by nearly half (to 12%, 13%, and 12%, respectively). Sodium Chloride interleukin 6 Mus musculus