Title : HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice.

Pub. Date : 2016 May

PMID : 26908870






1 Functional Relationships(s)
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1 Through a series of genetic silencing and adenoviral overexpression studies, we have defined GLUT1 as a critical downstream target of HIF-1alpha mediating high glucose-induced matrix expression through the NADPH oxidase isoform, NOX4. Glucose solute carrier family 2 (facilitated glucose transporter), member 1 Mus musculus