Title : [Sensitivity of esophageal squamous cell carcinoma cells to rapamycin can be improved by siRNA-interfered expression of p70S6K].

Pub. Date : 2015 Dec

PMID : 26887615






3 Functional Relationships(s)
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1 [Sensitivity of esophageal squamous cell carcinoma cells to rapamycin can be improved by siRNA-interfered expression of p70S6K]. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens
2 The results of tumor formation test in vivo showed that the inhibitory effect of rapamycin on tumor growth was stronger after the cells were transfected with p70S6K-siRNA, and the inhibition rate was 96.5%. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens
3 CONCLUSION: ESCC cells with different differentiation have different sensitivity to rapamycin, and p70S6K-siRNA can improve the sensitivity of cells to rapamycin in vitro and in vivo. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens